Publications

A Ugi Straightforward Access to Bis-β-lactam DerivativesSigmatropic Rearrangement-Based Synthesis of 4-Alkenyl-1,3-dithiol-2-ones
Cristina Cheibas, Marie Cordier, Yanyan Li, Laurent El Kaïm
Eur. J. Org. Chem. 2019, 10.1002/ejoc.201900678


Alternating Radical Stabilities: A Convergent Route to Terminal and Internal Boronates
Qi Huang, Jean Michalland and Samir Z. Zard
Angew. Chem. Int. Ed. 2019, 10.1002/ange.201906497


Sigmatropic Rearrangement-Based Synthesis of 4-Alkenyl-1,3-dithiol-2-ones
Pavels Ostrovskis, Andrey A. Mikhaylov and Samir Z. Zard
Org. Lett. 2019, 10.1021/acs.orglett.9b01157


One-pot Synthesis of Metastable 2,5-Dihydrooxepines Through Retro-Claisen Rearrangements: Methods and Applications
Wei Zhang, Emmanuel Baudoin, Marie Cordier, Gilles Frison and Bastien Nay
Chem. Eur. J. 2019, 10.1002/chem.201901675


Can the Ti(OiPr)4/nBuLi Combination of Reagents Function as a Catalyst for [2+2+2] Alkyne Cyclotrimerization Reactions ?
Gabriela Siemiaszko, Yvan Six
New Journal of Chemistry, 2018, 10.1039/C8NJ04931A


From Benzofurans to Indoles: Palladium-Catalyzed Reductive Ring-Opening and Closure via β-Phenoxide Elimination
Luca Alessandro Perego, Simon Wagschal, Raymond Grüber, Paul Fleurat-Lessard, Laurent El Kaim and Laurence Grimaud
Adv. Syn. Cat. 2018, Accepted, doi:10.1002/adsc.201801225


A Passerini/Michael pathway towards butyrolactones
Shuanglong Jia and, Laurent El-Kaïm
Eur. J. Org. Chem. 2018, Accepted, doi:10.1002/ejoc.201800958


Palladium triggered dienes formation from nitro allylic compounds: a versatile entry into naphthalene derivatives
Laurent El-Kaïm, Mansour Dolè Kerim, Shuanglong Jia, Sébastien Prévost and Chrysoula Theodorakidou
Chem. Comm. 2018, Accepted, doi:10.1039/C8CC06536E


Multifaceted study on a cytochalasin scaffold: lessons on reactivity, multidentate catalysis and anticancer properties
Mehdi Zaghouani, Oscar Gayraud, Vincent Jactel, Sébastien PRévost, Ambre Dezaire, Michèle Sabbah, Alexandre Escargueil, Thanh-Lan Lai, Christophe le Clainche, Nathalie Rocques, Stéphane Romero, Alexis Gautreau, Florent Blanchard, Gilles Frison and Bastien Nay
Chem. Eur. J. 2018, ASAP, doi: 10.1002/chem.201804023


Radical Fragment Coupling Route to Geminal Bis(boronates)
Qi Huand and Samir Z. Zard
Org. Lett. 2018, ASAP, doi: 10.1021/acs.orglett.8b02235


1,3-Dipolar Cycloadditions with azomethine ylide species generated from aminocyclopropanes
Andrzej Wolan, Justyna A. Kowalska-Six, Holisoa Rajerison, Michèle Césario, Marie Cordier and Yvan Six
Tetrahedron 2018, 74, 5248-5257.


Xanthate Mediated Incorporation of Quaternary Centers into Heteroarenes
Vincent Revil-Beaudard, Jean-Pierre Vors and Samir Z. Zard
Org. Lett. 2018, 20, 3531-3535.


The Xanthate Route to Ketones: When the Radical is better than the Enolate
Samir Z. Zard


Gold-catalyzed synthesis of b-trifluoromethylated of a,b-unsaturated ketones from CF3-substituted propargylic carboxylates and their reactivity in Diels-Alder reactions

Arnaud Boreux, Aubin Lambion, Dominic Campeau, Marina Sanita, Ruben Coronel, Olivier Riant and Fabien Gagosz


Proparylation of Ugi Amide Dianion: An Entry into Pyrrolidinone and Benzoindolizidine Alkaloid Analogues
Alaa Zidan, Marie Cordier, Abeer M. El-Naggar, Nour E. A. Abd El-Sattar, Mohamed Ali Hassan, Ali Khalil Ali And Laurent El-Kaïm
Org. Lett. 2018, 20, 2568-2571.


Intramolecular Aryne-Furan Cycloadditions for the Synthesis of Anticancer Naphthalimides
Sébastien Prévost, Ambre Sezaire and Alexandre Escargueil
J. Org. Chem. 2018, 83, 4871-4881.


(3 + 3) Cycloaddition of Oxyallyl Cations with Nitrones: Diastereoselective Access to 1,2-Oxazinanes
Marie Cordier and Alexis Archambeau
Org. Lett. 2018, Article ASAP, DOI: 10.1021/acs.orglett.8b00617

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Inexpensive Radical Methylation and Related Alkylation of Heteroarenes
Qi Huang and Samir Z. Zard
Org. Lett., 2018, 20, 1413-1416.

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Metal-Free Deamidative Ugi Access to Isoindolinones
Samira Baaziz, Mansour Solè Kerim, Marie Cordier, Lamourl Hammal and Laurent El Kaïm
Synlett 2018, DOI: 10.1055/s-0037-1610189.


4-Aminoprimidine librairies from the Ugi-Smiles reaction of thiouracils
Madjid Ait Sidhoum, Laurent El Kaïm and Laurence Grimaud
Tetrahedron 2018, in press, 10.1016/j.tet.2018.04.058.


Propargylation of Ugi Amide Dianion: An Entry into Pyrrolidinone and Benzoindolizidine Alkaloid Analogues
Alaa Zidan, Marie Cordier, Abeer M. El-Naggar, Nour E. A. Abd El-Sattar, Mahamed Ali Hassan, Ali Khalil Ali and Laurent El Kaïm
Org. Lett. 2018, 20, 2568-2571.


TiCl4 -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions
Sudipta Ponra, Aude Nyadanu, Sylvie Maurin, Laurent El Kaïm, Laurence Grimaud, Maxime R. Vitale
Synthesis 2018, 50, 1331-1342.


Mannich reaction of trifluoroacetaldehyde hydrazones, a useful entry to trifluoromethyl substituted heterocycles
Shuanglong Jia and Laurent El Kaïm
Org. Biomol. Chem. 2018, 16, 1457-1460.


Palladium-catalysed O -Allylation of α-Hydroxyphosphonates: An Expedient Entry into Phosphono-oxaheterocycles
Mansour Dolé Kerim, Martin Cattoen, Nicolas Fincias, Aurélie Dos Santos, Stellios Arseniyadis and Laurent El Kaïm
Adv. Synth. Catal. 2018, 360, 449-454.