In the group, we aim to develop new catalytic methods and to apply them to the synthesis of complex natural products. In particular, we are trying to discover regioselective C-H functionalizations of naphthalenes which is still an understudied skeleton. The objectives of this project is to be able to selectively functionalize different position of naphthalene derivatives thanks to metal-catalyzed C-H activation reactions. By combining these methodologies and bio-inspired approach, we also aimed at synthesizing complex aromatic polyketides.
In another project, we are trying to develop regioselective functionalization of aldehydes thanks to a transient directing group strategy.